08/03/26

Colorectal cancer mortality following an organized fecal immunochemical test-based screening program.

Bujanda, Luis; Val, Beatriz; Portillo Villares, Isabel; Idigoras-Rubio, Isabel; Banales, Jesus M; Gutierrez-Stampa, Maria A; Lopez de Munain, Arantza; Audicana, Covadonga; Calleja, Oscar; Cubiella, Joaquín; Izquierdo-Sanchez, Laura. JAMA Netw Open.

Summary

Organized screening can improve timely colorectal cancer diagnosis, but real-world population benefit depends on sustained participation and follow-up. This observational, population-based cohort, Spanish study evaluated mortality after implementation of a fecal immunochemical test (FIT)-based screening program. Screening was associated with substantially lower colorectal cancer mortality, supporting organized screening as a population-level diagnostic pathway while underscoring the importance of program implementation and follow-up.
Bujanda L, Val B, Portillo Villares I, et al. Colorectal cancer mortality following an organized fecal immunochemical test-based screening program. JAMA Netw Open. 2026;9(8):e2626951.