02/01/26

Eligibility and prognostic performance of smoking duration-based versus pack-year-based U.S. national lung cancer screening criteria across racial and ethnic groups.

Su, Chloe C; Ding, Victoria Y; Ten Haaf, Kevin; Wu, Julie T; Ödman, Neal D; Backhus, Leah M; Leung, Ann N; Lui, Natalie S; Haiman, Christopher A; Park, Sung-Shim Lani; Neal, Joel W; Meza, Rafael; Tammemägi, Martin C; Cheng, Iona; Le Marchand, Loïc; Wakelee, Heather A; Choi, Eunji; Han, Summer S. Ann Intern Med.

Summary

Screening guidelines can unintentionally acerbate racial disparities. This prospective study compares screening eligibility rules across diverse groups. Using a 30-year smoking history reduced racial disparities in who qualifies for lung cancer screening, especially for African Americans and Latinos. Risk-based approaches performed well overall but sometimes increased gaps.

Su CC, Ding VY, Ten Haaf K, et al. Eligibility and prognostic performance of smoking duration-based versus pack-year-based U.S. national lung cancer screening criteria across racial and ethnic groups. Ann Intern Med. 2026;179(2):196-206.