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02/01/26

Enhancement of patient-centered lung cancer screening: the MyLungHealth randomized clinical trial.

Kukhareva, Polina V; Li, Haojia; Balbin, Christian; Stevens, Elizabeth R; Mann, Devin M; Butler, Jorie M; Caverly, Tanner J; Del Fiol, Guilherme; Kaphingst, Kimberly A; Schlechter, Chelsey R; Tiase, Victoria L; Fagerlin, Angela; Zhang, Yue; Hess, Rachel; Flynn, Michael C; Reddy, Chakravarthy; Martin, Douglas; Warner, Phillip B; Nanjo, Claude; Choi, Joshua; Ngo-Metzger, Quyen; Kawamoto, Kensaku. JAMA Oncol.

Collection Topics
Big Three Conditions Health IT Tests, Screening, and Laboratory Processes
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Summary

Lung cancer screening with low-dose CT is underused in the US, partly due to incomplete smoking history records and limited time in primary care. This randomized study finds that adding a patient-facing tool to EHR workflows increased both identification of eligible patients and ordering of low-dose CTs compared to clinician tools alone, though the absolute increases were modest. More research is needed on intensive interventions to improve screening rates further.

Read the paper
Kukhareva PV, Li H, Balbin C, et al. Enhancement of patient-centered lung cancer screening: the MyLungHealth randomized clinical trial. JAMA Oncol. 2026;12(2):167-176.