Menu
Back to Equity and Access
04/22/26

Evaluating the impact of age on prostate cancer overdiagnosis using long-term follow-up from the CAP randomised trial.

Brentnall, Adam R; Rebolj, Matejka; Sasieni, Peter; Funston, Garth; Gabe, Rhian; Vickers, Andrew J. Int J Cancer

Collection Topics
Big Three Conditions Epidemiology Overdiagnosis
Share

Most recent

Frequency, Type, and Degree of Potential Harm of Adverse Safety Events among Pediatric Emergency Medical Services Encounters.

Cicero, Baird, Brown, et al., Prehosp Emerg Care.
09/11/26 Cognition and Decision Making Epidemiology

Primary care signals and diagnostic pathways before incident heart failure: a systematic scoping review.

Jerjes, El-Osta, Jhass, et al., J Prim Care Community Health.
09/09/26 Big Three Conditions Culture, Work System, and Implementation Epidemiology

Young women diagnosed with breast cancer: why is no one telling me to get a mammogram?

Jerome-D'Emilia, Suplee, Meyers, et al., J Nurs Scholarsh.
09/01/26 Big Three Conditions Equity, Access, and Timeliness

Summary

Overdiagnosis is a key harm of prostate cancer screening. Using long-term trial data and mortality estimates, this study finds that overdiagnosis was relatively low overall after a one-time PSA screening but rose sharply with age due to competing causes of death. Policies encouraging opportunistic screening, especially in older men, should be reconsidered.

Read the paper
Brentnall AR, Rebolj M, Sasieni P, et al. Evaluating the impact of age on prostate cancer overdiagnosis using long-term follow-up from the CAP randomised trial. Int J Cancer. 2026;159(5):1196-1203.