“One of the hardest things in medicine is challenging an initial diagnosis.” Interim diagnoses and missed opportunities for diagnosing cancer in primary care: a qualitative study.

Patients with undiagnosed cancer may first receive an alternative “interim” diagnosis, potentially delaying cancer detection. This study examines healthcare professionals’ views on when interim diagnoses occur, their impact on cancer diagnosis, and triggers for prompt review. Key factors included diagnostic uncertainty, non-specific symptoms, and remote consultations limiting information. While delays were common, safety-netting and team-based “fresh eyes” discussions enabled timely review.