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01/01/26

Risk of missed diagnoses when choosing non-operative management of pediatric uncomplicated appendicitis.

Guerra, Mary Elizabeth; Hickner, Brian T; Flores, Celia D; Fang, Mary E; Barclay, Charlene A; Graybill, Gabriella L; Lee, Timothy C; Vasudevan, Sanjeev A; Keswani, Sundeep G; Rodriguez, J Ruben. J Pediatr Surg.

Collection Topics
Epidemiology Tests, Screening, and Laboratory Processes
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Summary

Conservative disease management may limit diagnostic accuracy. This retrospective single-center study evaluated the incidence of unexpected diagnoses in children who underwent appendectomy for presumed uncomplicated appendicitis and examined related outcomes. While few patients were found to have alternative conditions, they were significant, highlighting the importance of surgical specimen evaluation and the risk of missing other pathologies with non-operative treatment.

Read the paper
Guerra ME, Hickner BT, Flores CD, et al. Risk of missed diagnoses when choosing non-operative management of pediatric uncomplicated appendicitis. J Pediatr Surg. 2026;61(1):162543.