03/18/26

From tool to teammate in a randomized controlled trial of clinician-AI collaborative workflows for diagnosis.

Everett, Selin S; Bunning, Bryan J; Jain, Priyank; Lopez, Ivan; Agarwal, Anup; Desai, Manisha; Gallo, Robert; Goh, Ethan; Kadiyala, Vinay B; Kanjee, Zahir; Koshy, Jacob M; Olson, Andrew; Rodman, Adam; Schulman, Kevin; Strong, Eric; Chen, Jonathan H; Horvitz, Eric. NPJ Digital Med.

Summary

AI performance shows promise as a tool to support diagnostic decision-making. This randomized controlled trial tests a custom system where the physician and AI give independent diagnostic opinions, then the AI combines them to highlight agreements and differences. Whether the AI went first or second, it improved the doctor’s accuracy, showing the potential of AI as a collaborative partner rather than a replacement for decision makers.

Everett SS, Bunning BJ, Jain P, et al. From tool to teammate in a randomized controlled trial of clinician-AI collaborative workflows for diagnosis. NPJ Digital Med. 2026;9(1):409.