02/14/26

Triple cardiovascular disease detection with an artificial intelligence-enabled stethoscope (TRICORDER) in the UK: a cluster-randomised controlled implementation trial.

Kelshiker, Mihir A; Bächtiger, Patrik; Petri, Camille F; Nakhare, Saloni; Mansell, Josephine; Chhatwal, Karanjot; Alrumayh, Abdullah; Zaman, Jahed; Shah, Moulesh; Young, Holly; Roy, Helena; Almonte, Melanie T; Costelloe, Céire; Razak, Yasmin; Majeed, Azeem; Howard, James P; Barton, Carys; Kramer, Daniel B; Plymen, Carla M; Peters, Nicholas S. Lancet.

Summary

Early detection of cardiovascular disease is a global health priority. This cluster-randomized trial assessed AI-enabled stethoscopes in UK primary care for heart condition detection. AI stethoscopes did not boost overall heart failure diagnoses over 12 months. The study design provides valuable real-world data on implementing AI healthcare innovations.

Kelshiker MA, Bächtiger P, Petri CF, et al. Triple cardiovascular disease detection with an artificial intelligence-enabled stethoscope (TRICORDER) in the UK: a cluster-randomised controlled implementation trial. Lancet. 2026;407(10529):704-715.