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07/03/26

The 5R's of large language model-assisted diagnosis: a practical framework for hospitalists.

Barish, Peter; Auerbach, Andrew D; Ranji, Sumant R. J Hosp Med.

Collection Topics
AI and Diagnosis Cognition and Decision Making
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Summary

LLMs are available to support diagnostic reasoning, but safe implementation is still evolving. This framework proposes five principles—using AI for the right patient, right question, right data, right workflow, and right oversight—to guide responsible clinical use. Rather than promoting indiscriminate use of AI, the authors emphasize maintaining clinician judgment, recognizing AI limitations, protecting patient privacy, and monitoring performance to reduce diagnostic risk.

Read the paper
Barish P, Auerbach AD, Ranji SR. The 5R’s of large language model-assisted diagnosis: a practical framework for hospitalists. J Hosp Med. Epub 2026 Jul 3.