03/05/26

From advice to action — real-world behavior of patients using an integrated diagnostic decision support system for navigating the health care system.

Cotte, Fabienne; Lourenço, Filipa Dias; Pereira, Miguel Paiva; Kini, Nisha; Schmude, Marcel; Pimenta, Andreia; Lemesiou, Athena; Gilbert, Stephen; Mehrali, Tauseef; Monteiro, Micaela Seemann; Flores, Pedro. NEJM AI.

Summary

The impact of AI-supported symptom assessment and follow-up services on patient behavior remains unclear. This Portuguese study surveyed patients before and after using an AI-supported digital assessment pathway and tracked actual behavior through electronic health records. Results showed differences in intentions pre and post AI-support symptom assessment including a decrease in unnecessary emergency department visits, as judged by a physician panel.

Cotte F, Lourenço FD, Pereira MP, et al. From advice to action — real-world behavior of patients using an integrated diagnostic decision support system for navigating the health care system. NEJM AI. 2026;3(4).