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05/14/26

The association between sepsis and diagnostic errors: a secondary analysis of the Utility of Predictive Systems for Diagnostic Error study.

Prasad, Priya A; Hubbard, Colin; Lee, Tiffany; Ranji, Sumant R; Raffel, Katie; Valdes, Gilmer; Boscardin, John; Dalal, Anuj K; Harris, Alysssa; Flynn, Ellen; Schnipper, Jeffrey L; Auerbach, Andrew. J Hosp Med.

Collection Topics
Culture, Work System, and Implementation Big Three Conditions Epidemiology
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Summary

Diagnostic error occurrence in hospitalized sepsis patients has yet to be determined. This retrospective cohort study at 29 academic medical centers found that sepsis patients who died in the hospital or were admitted to the ICU had diagnostic error rates similar to those without sepsis. Using Safer Dx and DEER taxonomy, the authors found sepsis was less strongly associated with diagnostic error when history-taking or consultation gaps were present, suggesting these errors reflect broader care problems rather than sepsis-specific factors.
Read the paper
Prasad PA, Hubbard C, Lee T, et al. The association between sepsis and diagnostic errors: a secondary analysis of the Utility of Predictive Systems for Diagnostic Error study. J Hosp Med. Epub 2026 May 14.