04/29/26

Human-AI collaboration in clinical reasoning: a UK replication and interaction analysis.

Healy, Justin; Kossoff, Jonathan; Lee, Matthew; Hasford, Christian. Diagnosis (Berl).

Summary

LLMs alone have illustrated the potential to outperform clinicians using the same LLM. This UK study confirmed prior US-based findings that physicians assisted by an LLM scored significantly worse than the LLM alone, although better than when using conventional non-LLM resources. This study provides a more in-depth look at the wide variation of how the physicians are engaging with LLMs which could explain their poorer performance.
Healy J, Kossoff J, Lee M, Hasford C. Human-AI collaboration in clinical reasoning: a UK replication and interaction analysis. Diagnosis (Berl). 2026 Apr 29.