05/27/26

Interpretive diagnostic error reduction: guideline update from the College of American Pathologists in collaboration with the Association of Directors of Anatomic and Subspecialty Pathology.

Dintzis, Suzanne M; Evans, Juanita J; Hernandez, Marisol; Kalicanin, Tanja; Lacchetti, Christina; Nakhleh, Raouf E; Otis, Christopher N; Pantanowitz, Liron; Parkash, Vinita; Raab, Stephen S. Archives of Pathology & Laboratory Medicine

Summary

Pathologist errors occur when diagnostic findings are missed during review of physical test specimens. This guideline update reviews the role of second opinions in detecting and preventing errors and calls for defined review procedures to improve safety. The authors examine emerging evidence on digital pathology and AI tools for error detection and case triage.

Dintzis SM, Evans JJ, Hernandez M, et al. Interpretive diagnostic error reduction: guideline update from the College of American Pathologists in collaboration with the Association of Directors of Anatomic and Subspecialty Pathology. Arch Pathol Lab Med. 2026;150(9):668-677.