Editor's Picks

Curated by the UCSF CODEX team, each Editor’s Pick features a standout study or article that moves the conversation on diagnostic excellence forward. These pieces offer meaningful, patient-centered insights, use innovative approaches, and speak to the needs of patients, clinicians, researchers, and decision-makers alike. All are selected from respected journals or outlets for their rigor and real-world relevance.  

Recent Editor's Picks

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Video Interview Ft. Dr. Mark Schlesinger
Coverage Uncertainty and Cancer Diagnosis: Insights from Dr. Mark Schlesinger
What happens when patients don't trust their health insurance to cover necessary care? According to new preliminary research from Yale University and partner institutions, uncertainty doesn't just affect how patients pay for care; it affects whether and when they seek care at all.  
October 2025

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Video Q&A ft. Shazia Siddique, MD, MSHP
Endoscopist deskilling risk after exposure to artificial intelligence in colonoscopy: a multicentre, observational study

Krzysztof Budzyń, Marcin Romańczyk, Diana Kitala, Paweł Kołodziej, Marek Bugajski, Hans O Adami, Johannes Blom, Marek Buszkiewicz, Natalie Halvorsen, Cesare Hassan, Tomasz Romańczyk, Øyvind Holme, Krzysztof Jarus, Shona Fielding, Melina Kunar, Maria Pellise, Nastazja Pilonis, Michał Filip Kamiński, Mette Kalager, Michael Bretthauer, and Yuichi Mori
Lancet Gastroenterology & Hepatology
August 12, 2025  

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“AI-based Clinical Decision Support for Primary Care: A Real-World Study” (pre-print)
Robert Korom, Sarah Kiptinness,  Najib Adan, Kassim Said, Catherine Ithuli, Oliver Rotich, Boniface Kimani, Irene King’ori, Stellah Kamau, Elizabeth Atemba, Muna Aden, Preston Bowman, Michael Sharman, Rebecca Soskin Hicks, Rebecca Distler, Johannes Heidecke, Rahul K. Arora, and Karan Singhal
aRxiv 
(Note: This is a pre-print that has not completed the peer review process.) 
July 22, 2025

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“Human–AI collectives most accurately diagnose clinical vignettes” 
Nikolas Zöller, Julian Berger, Irving Lin, Nathan Fu, Jayanth Komarneni, Gioele Barabucci, Kyle Laskowski, Victor Shia, Benjamin Harack, Eugene A. Chuh, Vito Trianni, Ralf H. J. M. Kurvers, and Stefan M. Herzog 
Proceeding of the National Academy of Sciences (PNAS)  
June 13, 2025  

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“A synthesized differential diagnosis is associated with fewer diagnostic errors compared to an inventorial list” 
Erica K. Sheline, Jan Leonard, Rebecca Helmuth, Kaitlin Widmer, Fidelity Dominguez, Mairead Dillon, Lilliam Ambroggio, and Joseph A. Grubenhoff 
Diagnosis (subscription required) 
April 4, 2025  

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“Dedicated AI Expert System vs Generative AI With Large Language Model for Clinical Diagnoses”
Mitchell J. Feldman, Edward P. Hoffer, Jared J. Conley, Jaime Chang, Jeanhee A. Chung, Michael C. Jernigan, William T. Lester, Zachary H. Strasser, & Henry C. Chueh
JAMA Network Open 
May 29, 2025

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Randomised controlled trial of audit-and-feedback strategies to reduce imaging overutilisation in the emergency department
Karl T Chamberlin, Christopher DiTullio, Jennifer Rossman, Bruce A Barton, Martin Reznek, & Kevin Kotkowski 
BMJ Quality & Safety (BMJ Qual Saf)  
April 3, 2025 

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Patient Perspectives on Delayed Specialty Follow-Up After a Primary Care Visit
Leonor Fernández, Dru Ricci, Amie Pollack, Maelys J. Amat, Meghan Drielak, Talya Salant, Gordon D. Schiff, Umber Shafiq, Scot B. Sternberg, James Benneyan, Mark Aronson, Erin Sullivan & Russell S. Phillips 
Journal of the American Board of Family Medicine (JABFM) 
April 2025 

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Real-time surveillance system for patient deterioration: a pragmatic cluster-randomized controlled trial
Sarah C. Rossetti, Patricia C. Dykes, Chris Knaplund, Sandy Cho, Jennifer Withall, Graham Lowenthal, David Albers, Rachel Y. Lee, Haomiao Jia, Suzanne Bakken, Min-Jeoung Kang, Frank Y. Chang, Li Zhou, David W. Bates, Temiloluwa Daramola, Fang Liu, Jessica Schwartz-Dillard, Mai Tran, Syed Mohtashim Abbas Bokhari, Jennifer Thate & Kenrick D. Cato
Nature Medicine​​​​
April 2, 2025

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“Sociodemographic biases in medical decision making by large language models”
Mahmud Omar, Shelly Soffer, Reem Agbareia, Nicola Luigi Bragazzi, Donald U. Apakama, Carol R. Horowitz, Alexander W. Charney, Robert Freeman, Benjamin Kummer, Benjamin S. Glicksberg, Girish N. Nadkarni & Eyal Klang
Nature Medicine
April 7, 2025

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"Comparison of Initial Artificial Intelligence (AI) and Final Physician Recommendations in AI-Assisted Virtual Urgent Care Visits" 
Zeltzer D, Kugler Z, Hayat L, Brufman T, Ilan Ber R, Leibovich K, Beer T, Frank I, Shaul R, Goldzweig C, Pevnick J.
Annals of Internal Medicine
April 4, 2025